عربي
Skip Navigation Links
UniversityExpand University
CollegesExpand Colleges
CentersExpand Centers
Admin. UnitExpand Admin. Unit
StaffExpand Staff
StudentsExpand Students
 
Skip Navigation LinksHome Research Research Papers Paper Description    
 
Skip Navigation Links.
 
Paper Description


Effet des venins de Macrovipera lebetina et de Cerastes cerastes sur l’adhésion de certaines lignées de cellules cancéreuses


Authors: Marrakchi Naziha,Sameh SARRAY, Jacques MARVALDI, Mohamed EL AYEB et José LUIS
Abstract: In this work, we provide experimental arguments in favor of the fact that
components from Macrovipera lebetina and Cerastes cerastes venoms bind to IGR39
melanoma cells but not to HT29D4 cells that derive from carcinoma adenome.
Furthermore, Macrovipera lebetina and Cerastes cerastes venoms inhibit the
adherence of IGR39 and HT 29-D4 to various extracellular matrix proteins.
Macrovipera lebetina and Cerastes cerastes venoms did not inhibit the non
specific adherence of IGR 39 cells to polylysine. In addition, binding of
components from Cerastes cerastes venom to IGR39 cells is inhibited by GRGDS
peptide and by monoclonal antibidy anti-av, while these two components have no
effect on the adherence of IGR39 to Macrovipera lebetina venom.
Published in: Pasteur Institute Archive;79():1-4
URL:
Copyright © 2010 Arabian Gulf University Contact: Tel:17239999, Fax:17272555 | Home | Location | site map| عربي |