عربي
Skip Navigation Links
UniversityExpand University
CollegesExpand Colleges
CentersExpand Centers
Admin. UnitExpand Admin. Unit
StaffExpand Staff
StudentsExpand Students
 
Skip Navigation LinksHome Research Research Papers Paper Description    
 
Skip Navigation Links.
 
Paper Description


Antigen-specific influence of GM/KM allotypes on IgG isotypes and association of GM allotypes with susceptibility to Plasmodium falciparum malaria.


Authors: Giha HA, Nasr A, Iriemenam NC, Arnot D, Troye-Blomberg M, Theander TG, Berzins K, ElGhazali G, Pandey JP.
Abstract: BACKGROUND: Plasmodium falciparum malaria is a complex disease in which genetic and environmental factors influence susceptibility. IgG isotypes are in part genetically controlled, and GM/KM allotypes are believed to be involved in this control.

METHODS: In this study, 216 individuals from Daraweesh, an area of seasonal malaria transmission in Sudan, were followed for nine years for malaria infection. Total IgG and IgG isotypes against four malaria antigens, MSP2-3D7, MSP2-FC27, AMA1, and Pf332-C231 were measured in plasma obtained from the cohort at the end of the study, during the dry malaria-free period. The GM/KM allotypes of the donors were determined.

RESULTS: The GM 1,17 5,13,14,6 phenotype was associated with a higher incidence of malaria compared with the non-1,17 5,13,14,6 phenotypes (P = 0.037). Paradoxically, the carriers of the GM 1,17 5,13,14,6 phenotype had significantly higher baseline levels of total IgG and non-cytophilic IgG isotypes as compared to non-carriers. The KM allotypes influence on IgG isotypes level was limited. Finally, the differences in the baseline concentrations of total IgG and IgG isotypes between the different GK/KM phenotype carriers were antigen-dependent.

DISCUSSION: The results show that GM but not KM allotypes appeared to influence host susceptibility to uncomplicated malaria as well as the antibody profile of the donors, and the carriers of the GM 1,17 5,13,14,6 phenotype were the most susceptible

CONCLUSIONS: The GM allotypes have significant influence on susceptibility to uncomplicated P. falciparum malaria and antigen-dependent influence on total IgG and IgG subclasses.
Published in: Malar J.;():
URL: http://www.ncbi.nlm.nih.gov/pubmed/20028548
women who like to cheat my husband cheated on me dating for married people
spy dialer android read spy android app
married men cheat go why wife cheat
would my boyfriend cheat parentpower.com cheated on my boyfriend
wife wants to cheat site my wife cheated now what do i do
how do you know your wife cheated site why do i want to cheat on my wife
i cheated my husband site did my husband cheat
i cheat on my girlfriend open is my girlfriend cheated on me
i cheated on my boyfriend with a black guy site i have cheated on my boyfriend
signs of a cheater click catch a cheat
indian sex stories read black female slave sex stories
free sex stories with pictures tolobel.com free online gay sex stories
hindi erotic sex stories tolobel.com food sex stories
grown women and their fathers who have consenual sex stories click gay sex stories gay erotic stories stories male fiction novels erotica
abortion facts bigwindcn.com hillcrest abortion clinic
walgreens coupon code photos read rite aid makeup coupons
cvs print coupon read free prescription drug discount card
coping with abortion abortion pill what happens after an abortion
valtrex sporturfintl.com viagra 25mg
free cialis samples coupon carp-fishing.nl free prescription drug cards
rite aid store coupons rite aid coupon matchups rite aid prescription transfer coupon
metronidazole 400mg sumatriptan amoxicillin
coupon viagra markthrice.com viagra coupon free
discount coupons for prescriptions read transfer prescription coupon
viagra savings and coupons floridafriendlyplants.com pet prescription discount card
coupons for prescription drugs discount coupons for viagra drug coupons
drug coupon read coupons viagra
viagra trial coupon softballspa.com free prescription cards
viagra coupons 2016 blog.brunothalmann.com 2016 viagra coupon
can i take levitra viagra in same day can i take levitra viagra in same day can i take levitra viagra in same day
can i take imodium ad if i am pregnant canitake.net can i take imodium ad if i am pregnant
can i take antabuse and naltrexone can i take antabuse and naltrexone can i take antabuse and naltrexone
can i take antabuse and naltrexone can i take antabuse and naltrexone can i take antabuse and naltrexone
abortion pill abortion pill abortion pill
cialis dosage amounts open cialis dose 40
cialis.com coupons manufacturer coupons for prescription drugs coupon for prescription
prescription coupons is-aber.net cialis coupons online
prescriptions coupons is-aber.net cialis coupon free
augmentin duo augmentin duo augmentin bis
aerius heuschnupfen 2minapp.azurewebsites.net aerius marine
losartankalium losartan 50 mg losartankalium teva 50 mg
fusidinezuur blog.jp-sa.org fusidinezuur voetschimmel
augmentin injectable augmentin augmentin sirop
buscopan compositum idiotygenii.com buscopan spc
cozaar dci cozaar posologie cozaar compendium
lilly cialis coupon printable coupons for cialis coupons for drugs
neurontin 600 milligram williamgonzalez.me neurontin alcohol
cialis.com coupons pureheartvision.org cialis coupons from lilly
does insurance cover abortion read abortion info
free cialis coupon 2016 cialis savings and coupons free coupon for cialis
cialis.com coupons coupon for free cialis cialis manufacturer coupon
coupons for cialis 2016 cialis coupons and discounts discount coupons for cialis
clomid clomid cycle clomid tapasztalatok
cialis savings and coupons discount coupon for cialis cialis coupons free
pro-choice abortion facts having an abortion how many abortions can a woman have
concord neo concord fusion concordia
average abortion pill cost anti abortion facts abortion price
losartankalium krka bivirkninger losartankalium losartan pro medicin
coupon for free cialis coupons prescriptions prescriptions coupons
cialis 2015 coupon sfmcouriers.com cialis coupon 2015
vermox sirup cijena vermox suspenzija vermox sirup cijena
lilly coupons for cialis cialis coupons free cialis coupons free
priligy resepti priligy priligy 30 mg
cialis coupons free coupons for cialis printable coupon for cialis
amoxicillin al 1000 amoxicillin endikasyonlar amoxicillin 500 mg
amoxicillin dermani haqqinda americanstreethockey.com amoxicillin 500 mg
cialis coupons and discounts prescription discount coupon prescription coupons
free abortions the cost of abortion free abortions
acetazolamide migraine acetazolamide acetazolamide migraine
opiate blocker shot vivitrol naltrexone alcoholism medication does naltrexone cause weight loss
abortion pill alternatives cheap abortion pill clinics cons of abortion pill
teenage abortions unwanted pregnancy options abortion in the first trimester
vermox sirup cijena vermox cijena vermox tablete doziranje
cialis nedir onlineseoanalyzer.com cialis 5 mg
prescription savings cards free drug coupons print free coupons
clomid tapasztalatok clomid testosterone clomid cycle
viagra online philhustead.com viagra online
different types of abortion pill abortion pill stories abortion pill methods
amoxicillin dermani haqqinda amoxicillin dermani haqqinda amoxicilline
prescription transfer coupon albayraq-uae.com coupon cialis
viagra wiki viagra helyett viagra pret
the cost of abortion how do abortion pill work pro choice abortion pill
cialis coupons from manufacturer cialis coupon lilly prescription discount coupons
discount card prescription free grocery coupons viagra sample coupon
abortion pill services abortion pill law how to get an abortion pill
cost for an abortion facts about abortion pill how late can you get an abortion pill
amoxicillin dermani haqqinda amoxicillin 500 mg amoxicillin dermani haqqinda
vermox truonggiang.net vermox alkohol
abortion pill cost airascatering.com abortion pill pros and cons
types of abortion pill abraham.thesharpsystem.com pro choice abortion pill
printable coupons for cialis armyrotc.uga.edu cialis discounts coupons
non surgical abortion pill anti abortion pill where to get an abortion pill
acetazolamide blood brain barrier blog.bjorback.com acetazolamide blood brain barrier
cialis discount coupon cialis trial coupon prescription coupon card
Copyright © 2010 Arabian Gulf University Contact: Tel:17239999, Fax:17272555 | Home | Location | site map| عربي |